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OCR: De The cause of the thyroid dysfunction ma igns of clinically apparent (for example, the eye required toGraves' disease). Serological tests may be proid TSH confirm the presence of autoimmune th disease. With the availability of sensitive TSH assays that are capable of recognising low inga levels, it is rarely necessary to resort to u est. It thyrotrophin-releasing hormone (TRH) ne is not should be noted that a low TSH level ald sufficient to establish a diagnosis of re seen in hyperthyroidism, since low TSH levels a ndividualsoccasional normal subjects and in some with severe non thyroidal illness. See also: . Tests of the Thyroid-Pituitary Axis